People Cutaneous Oncodermatology Operations USCOM An operating Formula

Fluorescence emission difference (FED) microscopy, as an emerging super-resolution imaging modality, uses double-exposure and subtraction between double-exposed fluorescence images to achieve high spatial resolution beyond the diffraction limit. Here we report on a new FED imaging approach with a single-exposure scheme based on dynamic cylindrical-vector fields, where the fluorescence excitation beam can be switched between radial and azimuthal polarization states at a designated high radio frequency. Lateral spatial resolution of $\sim \lambda/4$ is achieved. Being able to integrate with lock-in amplifier detection, the proposed method will find promising applications for high-speed fluorescence imaging with improved signal-to-noise ratio.Direct generation of ultrashort few-optical-cycle pulses in various wavelength regions has attracted great attention in recent decades. In this paper, generation of less than five-optical-cycle pulses from a Kerr-lens mode-locked $\rm Yb\rm CaYAlO_4$ laser is demonstrated. Pumped by a 976 nm fiber laser, stable near-Fourier-transform-limited ultrashort soliton pulses centered around 1080 nm with a repetition rate of $\sim113.7\;\rm MHz$ were obtained. The obtained pulses have a pulse duration as short as 17 fs if a $\rm Sech^2$-shaped pulse profile is assumed, corresponding to about 4.68 optical cycles. To the best of our knowledge, this is the shortest pulse directly generated from mode-locked rare-earth-doped solid-state oscillators.We demonstrate a large-area fabrication process for optical metasurfaces utilizing reusable SiN on Si nanostencils. To improve the yield of the nanostencil fabrication, we partially etch the front-side SiN layer to transfer the metasurface pattern from the resist to the nanostencil membrane, preserving the integrity of the membrane during the subsequent potassium hydroxide etch. To enhance the reliability and resolution of metasurface fabrication using the nanostencil, we spin coat a sacrificial layer of resist to precisely determine the gap between the nanostencil and the metasurface substrate for the subsequent liftoff. 1.5 mm diameter PbTe meta-lenses on $\rmCa\rmF_2$ fabricated using nanostencils show diffraction-limited focusing and focusing efficiencies of 42% for a 2 mm focal length lens and 53% for a 4 mm focal length lens. The nanostencils can also be cleaned using chemical cleaning methods for reuse.We demonstrate a narrow linewidth vertical-cavity surface-emitting laser (VCSEL) by injecting resonant optical feedback into the lasing cavity. A single longitudinal mode VCSEL with a Lorentzian linewidth of 32.6 kHz and a purified optical spectrum is experimentally achieved by an on-chip microring add-drop filter with a quality factor of 1.36 million, where the feedback level is $-47.77\;\rmdB$. The frequency noise spectrum of the VCSEL demonstrates that the thermo-optic effect in the microring resonator can also stabilize the lasing frequency. A VCSEL with narrow linewidth and stable frequency provides a high-performance light source for a single VCSEL or VCSEL array-based application.Optical spin or circular polarization provides a new degree of freedom to control light-matter interaction in the fundamentals and applications of light. To broaden the bandwidth of chiral (spin-controlled) coupling in photonic integrated circuits, we propose fork-type inversely tapered nanowire waveguides to compensate for the out-of-step phase evolution of adiabatic coupling between $\rm TE_0$ and $\rm TM_0$ ($\rm TE_1$) modes excited from the $x$- and $y$-polarization components of spin polarized light in free space, respectively. We design and simulate two kinds of devices based on air and $\rm Si_3\rm N_4$ up-claddings to show the feasibility of broadening the bandwidth of chiral silicon photonic circuits by using fork-type inverse tapers. Numerical results show that the bandwidth can approach 70 nm under high directionality of above 0.90. see more This broadband chiral coupling via the new phase synchronizing technique with fork-type inverse tapers may pave the way to develop on-chip spin photonics or polarization-based photonic integrated devices.A Kerr-lens mode-locked (KLM) thin-disk laser with YbLuAG ceramic was demonstrated. YbLuAG ceramic is an attractive material for high-power lasers due to its high thermal conductivity and large emission cross section. The highest output power of 17 W with a pulse duration of 130 fs was achieved. Moreover, the pulse duration of 88 fs was also obtained with a high-Q factor cavity. To the best of our knowledge, this is the first demonstration of a KLM thin-disk laser based on YbLuAG, including both ceramic and single crystal. The results show the usefulness of ceramic thin disks for high-power ultrashort pulse laser sources.10-kHz hydroxyl radical (OH) two-color planar laser-induced fluorescence (TC-PLIF) thermometry was demonstrated with a single burst-mode optical parametric oscillator (OPO) and a single camera. A fast, dual-wavelength switched seed laser enabled a high-energy, high-repetition-rate burst-mode laser to generate two 10-kHz pulse trains at wavelengths of $\sim354.8\;\rm nm$. The two pulse trains are colinear with 3 µs time interval between the pulse pairs. The injection-seeded OPO efficiently converts the burst-mode laser output to 285.62 and 285.67 nm to excite the $Q_2(12)$ and $P_1(8)$ OH transitions. PLIF images were collected from each of the two excitation transitions, and intensity ratios from the images were used to determine local temperatures. The development of fast, dual-wavelength switching, burst-mode OPO technology significantly reduces the experimental complexity of the high-speed TC-PLIF thermometry and simplifies its implementation in harsh combustion and flow test facilities.Optical frequency conversion provides a fundamental and important approach to manipulate light in frequency domain. In such a process, manipulating the frequency of light without changing information in other degrees of freedom of light will enable us to establish an interface between various optical systems operating in different frequency regions and have many classical and quantum applications. Here we experimentally demonstrate a frequency conversion with maintaining polarization and orbital angular momentum (OAM) by successfully upconverting various polarization-OAM composite states in a nonlinear Sagnac interferometer. Our scheme offers a new possibility for building different wave band interfaces in more degrees of freedom.