Antifibrotic and also anthelminthic aftereffect of casticin about Schistosoma mansoniinfected BALBc these animals

Pin inhalation is an accidental entry of a pin into the respiratory passages. This study aims to shed the light on pin inhalation as a hazard and show the magnitude of such preventable thoracic problem and determine the safest method of management.
This is a retrospective single center case series, conducted during 18 month period from January 2016 to April 2017, All patients with pin inhalation had been collected and analyzed according to the age, gender, time between aspiration to presentation and symptoms and signs, number of attempts, bronchoscopic or open removal of the pins with complications.
The total number of patients in this study was 162. The mean age was 11years. Pin inhalation accident was more common in patients less than 10 years in males and less than 20 years in females. The most common gender was female (73%). The most common presenting symptom was cough (54%). The left tracheobronchial tree was the most common site for pin lodgment 107 (67.3%) followed by the right side 23 (14.4%). The majority of the pins were extracted in one piece (94%). Thoracotomy was done in one patient, no death reported.
Sharp pin inhalation is a serious hazard and can have lethal outcome. learn more History is the major parameter to start the diagnosis of pin inhalation and radiography is the gold standard to confirm the diagnosis.
Sharp pin inhalation is a serious hazard and can have lethal outcome. History is the major parameter to start the diagnosis of pin inhalation and radiography is the gold standard to confirm the diagnosis.•Declining financial opportunities along with clinical hour requirements to generate revenue produces role strains for surgeon-scientists.•Adjusting the current workload model to include protected research time and devising financial support through partnerships can improve strain on surgeon-scientists.•Early integration of research into medical education along with networking and mentorship can inspire future surgeon-scientists, potentially leading to positive career trajectories.
Breast cancer disease is the most common cancer in US women and the second cause of cancer death among women.
To compare and evaluate the performance and accuracy of the key supervised and semi-supervised machine learning algorithms for breast cancer prediction.
We have used nine machine learning classification algorithms for supervised (SL) and semi-supervised learning (SSL) 1) Logistic regression; 2) Gaussian Naive Bayes; 3) Linear Support vector machine; 4) RBF Support vector machine; 5) Decision Tree; 6) Random Forest; 7) Xgboost; 8) Gradient Boosting; 9) KNN. The Wisconsin Diagnosis Cancer dataset was used to train and test these models. To ensure the robustness of the model, we have applied K-fold cross-validation and optimized hyperparameters. We have evaluated and compared the models using accuracy, precision, recall, F1-score, and ROC curves.
The results of all models are inspiring using both SL and SSL. The SSL has high accuracy (90%-98%) with just half of the training data. The KNN model for the SL and logistic regression for the SSL achieved the highest accuracy of 98.
The accuracies of SSL algorithms are very close to the SL algorithms. The accuracies of all models are in the range of 91-98%. SSL is a promising and competitive approach to solve the problem. Using a small sample of labeled and low computational power, the SSL is fully capable of replacing SL algorithms in diagnosing tumor type.
The accuracies of SSL algorithms are very close to the SL algorithms. The accuracies of all models are in the range of 91-98%. SSL is a promising and competitive approach to solve the problem. Using a small sample of labeled and low computational power, the SSL is fully capable of replacing SL algorithms in diagnosing tumor type.
Sclerosing pneumocytoma (SP) is a rare benign neoplasm of the lung with peak age incidence in middle aged-women. Here we report, for the first time in the literature, a case of a 1-year-old girl with SP.
A 1-year-old girl was reported to emergency department for massive hemoptysis. After admission, the patient had a three-days episode of melena, with normal body temperature and generally stable condition.
Fiberoptic bronchoscopy was normal. MSCT was done along with angiography and Three-Dimensional Reconstruction which revealed a well-circumscribed round mass with well-defined borders located near the vessels in the upper lobe of left lung. Anatomic lingula resection was performed. Hilar node was also resected. The histopathological examination confirmed the presence of SP. Fourteen months postoperatively, the patient was in a good health with no clinical or radiological evidence of recurrence.
SP is a rare benign tumor which usually presents in middle aged-women asymptomatically or with nonspecific symptoms. We report this case to highlight that SP should be considered in cases of hemoptysis in young children.
SP is a rare benign tumor which usually presents in middle aged-women asymptomatically or with nonspecific symptoms. We report this case to highlight that SP should be considered in cases of hemoptysis in young children.
To perform a systematic review and meta-analysis of randomized controlled trials that examined remdesivir treatment for COVID-19.
A systematic literature search was performed using Pubmed, Embase, and ClinicalTrials.gov to identify studies published up to October 25, 2020 that examined COVID-19 treatment with remdesivir. A total of 3 randomized controlled trials that consisted of 1691 patients were included in the meta-analysis.
The odds for mechanical ventilation (MV) or extracorporeal membrane oxygenation (ECMO) following treatment was significantly lower in the remdesivir group compared to the control group (OR=0.48 [95% CI 0.34; 0.69],
<0.001). The odds of early (at day 14/15; OR=1.42 [95% CI 1.16; 1.74],
<0.001) and late (at day 28/29; OR=1.44 [95% CI 1.16; 1.79],
=0.001) hospital discharge were significantly higher in the remdesivir group compared to the control group. There was no difference in the odds for mortality in patients treated with remdesivir (OR=0.77 [95% CI 0.56; 1.06],
=0.