Under the sea ENDOSCOPIC MUCOSAL RESECTION Pertaining to Tiny Arschfick NEUROENDOCRINE TUMORS

Individuals with opioid use disorder (OUD) have high prevalence of smoking and poor cessation outcomes. Data suggest that smokers with OUD may experience heightened nicotine reinforcement and more severe tobacco withdrawal compared to smokers without OUD. The Food and Drug Administration is currently considering reducing the nicotine content of cigarettes to reduce smoking prevalence and smoking-related disease. It is critical to understand the effects of reduced nicotine content cigarettes (RNCCs) on tobacco withdrawal in this subgroup. In this secondary analysis, we investigated the ability of RNCCs to attenuate acute tobacco withdrawal and craving severity in smokers with OUD versus those without substance use disorders (SUDs). Smokers maintained on methadone or buprenorphine (opioid-maintained [OM]; n = 65) versus without other SUDs (i.e., non-SUD; n = 135) completed 5 laboratory sessions wherein they smoked their usual brand (UB) or a research cigarette varying in nicotine content (0.4, 2.4, 5.2, 15.8 mg/g of tobacco) under double-blind, acute abstinence conditions. click here Participants completed the Minnesota Tobacco Withdrawal Scale, including a desire to smoke (craving) item, before and every 15 min for 1 hr following smoking each cigarette. Tobacco withdrawal and craving did not differ significantly by OM status in response to UB or RNCCs. In addition to the Dose × Time interaction, greater depression and cigarette dependence consistently predicted withdrawal and craving (ps less then .05). Across all cigarettes, tobacco withdrawal and craving did not significantly differ by OM status, suggesting that smokers receiving opioid agonist treatment may respond favorably to RNCCs. Additional studies with larger and more diverse samples are needed to address this question more definitively. (PsycINFO Database Record (c) 2020 APA, all rights reserved).Cognitive behavioral therapy (CBT) has been found to be very effective in reducing many forms of mental illness, but much less is known about whether CBT also promotes mental health or well-being. The goals of the present study were to (a) quantify the magnitude and timing of changes in overall well-being and specific facets of well-being during different CBTs for anxiety disorders, (b) determine whether these effects vary across transdiagnostic and disorder-specific CBT, and (c) examine how changes in well-being during treatment relate to changes in anxiety. A total of 223 adults (55.6% female, Mage = 31.1 years) were randomized to 1 of 5 CBT protocols for anxiety disorders at an outpatient clinic. Analyses included standardized mean gain effect sizes (ESsg) and latent growth curve modeling. Moderate-to-large increases in overall well-being and the 3 components of subjective, psychological, and social well-being were observed, mainly during the second half of CBT, and these increases were maintained at a 6-month follow-up. The magnitude of effects was comparable for transdiagnostic and disorder-specific CBT protocols and greater than in the waitlist condition. Parallel process latent growth curve models indicated that trajectories of change in well-being across treatment were strongly correlated with trajectories of change in clinician-rated and self-reported anxiety. Together, these findings suggest that different CBT protocols for anxiety consistently produce robust and lasting changes in well-being, and these changes are strongly linked to changes in anxiety during treatment. (PsycINFO Database Record (c) 2020 APA, all rights reserved).OBJECTIVE This study presents a prospective evaluation of the contribution of criminogenic factors, psychiatric symptomatology, and neighborhood-level factors to risk for self-reported gun violence by adolescents with criminal justice involvement. HYPOTHESIS We hypothesized that elevated psychiatric symptom clusters would be associated with increased risk for gun violence after accounting for criminogenic factors and that neighborhood contextual variables would contribute independently to gun violence risk controlling for criminogenic and psychiatric factors. METHOD Data were drawn from the Pathways to Desistance study (Mulvey et al., 2004), a previously collected, longitudinal evaluation of 1,354 adolescents with felony or weapons-based misdemeanor convictions. Participants were located in Arizona and Pennsylvania and aged 14-18 at baseline. The majority identified as male (86.4%) and Black (41.4%) or Hispanic (33.5%). Participants completed interviews at baseline and follow-up over 7 years. This study drew indicators of criminogenic factors, psychiatric factors, ratings of neighborhood context, and self-reported offending. We used discrete time survival analysis to prospectively evaluate the contribution of independent variables to time to gun violence. RESULTS The presence of self-reported threat control override symptoms represented a 56% increase in risk controlling for demographic and criminogenic factors, odds ratio = 1.56, 95% confidence interval [1.11, 2.18]. Ratings of higher neighborhood gun accessibility represented almost 2.5 times increased risk for self-reported gun violence controlling for demographic, criminogenic, and psychiatric factors, odds ratio = 2.48, 95% confidence interval [1.60, 3.85]. CONCLUSIONS Results suggest that consideration of both environmental and individual-level factors hold importance for management of community risk and public safety for adolescents with criminal justice involvement. (PsycINFO Database Record (c) 2020 APA, all rights reserved).Presents an obituary for Nancy M. Petry (1968-2018). Until the time of her death, she was the editor of Psychology of Addictive Behaviors. Nancy had 371 articles published, an average of more than 15 articles per year since her career began. She was the principal investigator on 28 grants from the National Institutes of Health, author of three books, and editor of four more. (PsycINFO Database Record (c) 2020 APA, all rights reserved).This special issue of Psychology of Addictive Behaviors honors the life and work of a beloved friend, colleague, and mentor, Dr. Nancy M. Petry, who died on July 17, 2018 of breast cancer. At the time of her death, Dr. Petry was the editor of this journal. We were gratified to receive many submissions for this issue, resulting in an outstanding set of 24 selected articles. These articles span the multiple areas of addiction research to which Dr. Petry made key contributions, and this introduction highlights her work in these areas. The topic areas in this issue include behavior analysis and behavior pharmacology; contingency management-randomized controlled trials; contingency management-implementation and dissemination; demographic predictors of outcomes across multiple clinical trials; reinforcer pathology and decision making; and gambling. We can only imagine what great work Dr. Petry would have contributed in the future, but the research presented in this issue makes clear that her legacy and impact will continue to grow.